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Study in Ghana finds gaps in biopsy uptake and long delays to treatment initiation at district hospitals

January 02, 2026 | National Cancer Institute (NCI), National Institutes of Health (NIH), Department of Health and Human Services (HHS), Executive, Federal


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Study in Ghana finds gaps in biopsy uptake and long delays to treatment initiation at district hospitals
Dr. Clement t Nair presented findings from a cohort study examining breast cancer diagnostic and referral pathways at district-level hospitals in Ghana. The study—linked to the African Breast Cancer outcome disparities program—enrolled 244 women in the reported cohort and used face-to-face interviews, pathology abstraction and follow-up to measure time-to-diagnosis and time-to-treatment.

Key reported metrics included a median 14 days from initial facility contact to histopathological diagnosis and a median 76 days to treatment initiation. Nair highlighted uptake gaps: biopsy uptake and subsequent treatment initiation were lower than desired at district facilities, despite "excellent" pathology turnaround times reported by the project team. Major barriers included travel distance, referral navigation, and financial constraints; the study used SMS/transport and active recruitment strategies to maintain the cohort.

Nair recommended streamlining referral pathways, expanding diagnostic services outside tertiary centers, and maintaining active recruitment and registry infrastructure to track outcomes in non-capital settings. The presenter credited WHO’s Global Breast Cancer Initiative as an informing framework for targets on early detection and treatment timelines.

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