Trump announces trumprx.gov, says most-favored-nation deals will sharply cut U.S. drug prices

President Donald J. Trump announced the launch of trumprx.gov onstage, saying the site will offer steep discounts on dozens of commonly used prescription drugs and that the reductions stem from "most favored nation" pricing his administration negotiated with drugmakers.

"It's called trumprx.gov," Trump said. "Starting tonight, dozens of the most commonly used prescription drugs will be available at dramatic discounts for all consumers throughout a new website." He described the effort as "the largest reduction in prescription drug prices in history," and said the United States would pay "the lowest price paid by any other country."

Trump framed tariffs as the enforcement mechanism that compelled agreements overseas. He said countries that did not raise prices faced U.S. tariffs and claimed that, in many cases, foreign prices "went up by double, triple" while U.S. prices fell. He repeatedly cited percentage and dollar examples in the speech.

Trump named specific medicines and companies as examples. He said Novo Nordisk would cut the price of Ozempic to $199 (from "more than $1,000") and Wegovy to $199 (from "more than $1,300"); he said Eli Lilly would reduce a common insulin from $200 to $25; and he said AstraZeneca would lower a common inhaler from $458 to $51. Trump also said EMD Serono would dramatically cut the price of the IVF drug Gonal-f, which he described as previously among the most expensive in the developed world. The transcript records these claims but does not include independent price confirmations.

Trump invited doctor Mehmet Oz, introduced onstage as "administrator of the Centers for Medicare and Medicaid Services," to demonstrate the website. In the demonstration, Oz searched for a drug, showed an entry labeled an "83% off" discount, and explained that users receive a coupon they can print or add to a mobile wallet and present at the pharmacy to receive the discounted price. Oz said the site would launch with over 40 medications and that more drugs would be added "week over week."

A woman identified in the transcript as Catherine, who said she is a military spouse and has been navigating infertility and IVF for five years, gave a brief testimony. She said medications such as Gonal-f had been essential to treatment and that lower prices could make continuing therapy feasible for families facing large out-of-pocket costs.

The transcript records additional claims: that "16 of the 17 largest pharmaceutical companies have signed agreements," that manufacturers will invest "hundreds of billions" to build U.S. plants (Trump cited Eli Lilly building "6 plants"), and an assertion that tariffs were producing more than $18,000,000,000,000 in receipts for the United States. None of those figures or the scope of the agreements were independently verified in the event transcript.

The event closed with Trump thanking designers and staff involved in the site, including Joe Gebbia of the National Design Studio and Ed Korostein, and with praise for Bobby Kennedy Junior as an advocate; the transcript records no formal vote, rule change or regulatory text.

What remains unclear from the transcript is how the pricing arrangements will be implemented in practice, how pharmacies and insurers will coordinate coupon and reimbursement mechanics, which exact drugs and formulations are included at launch beyond a general statement of "over 40 medications," and whether federal or statutory authority was changed to permit the pricing approach described. The transcript records statements of intent and claimed agreements but does not include documentation of signed contracts, implementing regulations, or outside verification of price changes.

The next procedural step recorded in the event was the site demonstration and an invitation for the public to visit trumprx.gov to view prices and obtain coupons; no formal rulemaking, vote or other government action appears in the transcript.