Company reports respiratory microbiome products cut infected lung tissue in cattle by up to 60%

Chris Belnap, founder of Resilient Biotics, described the company's respiratory microbiome strategy for livestock and the datasets behind it: a sample biobank and isolate collection totaling more than 11,000 samples and isolates and over 3,000 omics files. He said the company uses those resources to select commensal strains, screen for mobilizable resistance genes, and design consortia for testing in animals.

Belnap reported that targeted intranasal delivery of selected live microorganisms has demonstrated efficacy in large-animal testing: "we've been able to demonstrate up to a 60 percent reduction in infected lung tissue" in bovine respiratory disease models, and single-dose administration at predictable high-risk timepoints is a strategic goal to enable on-farm use and reduce routine antibiotic reliance.